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Vaginal & vulval health · 4 min read

Thrush cream vs tablet — which to choose

Thrush can be treated with creams, pessaries, or oral tablets. Here's how they compare and how to decide which is right for you.

Dr Amelia HartleyUpdated July 2026
Medically reviewed by Dr Amelia Hartley, AHPRA-registered GP — Last reviewed July 2026
Thrush cream vs tablet — which to choose

Creams and pessaries

Antifungal creams (like clotrimazole) are applied to the vulva to relieve external itching and soreness. Pessaries are inserted into the vagina to treat the infection at its source. They're often used together for the best results.

These treatments are available over the counter and work well for many women. The downside is they can be messy and take a few days to fully resolve symptoms.

Oral tablets

An oral antifungal tablet (fluconazole) treats the infection from the inside out. It's convenient — a single dose is often enough — and tends to work quickly. Some women prefer the simplicity of a tablet over creams and pessaries.

Fluconazole is available over the counter but may not be suitable for everyone — for example, it can interact with certain medications and isn't recommended during pregnancy. Your pharmacist or GP can advise.

Which is right for you?

Both treatments are effective. The choice often comes down to personal preference, whether you're pregnant (creams and pessaries are preferred), and whether you prefer the convenience of a tablet or the soothing effect of a cream.

If this is your first episode, or if treatment hasn't worked, see a GP. They can confirm it's thrush and recommend the most appropriate treatment for your situation.

References & sources

This content is general information and not a substitute for individual medical advice. Please consult a GP for your personal situation.

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